Antidepressants Fluoxetine Mediates Endoplasmic Reticulum Stress and Autophagy of Non-Small Cell Lung Cancer Cells Through the ATF4-AKT-mTOR Signaling Pathway

• 主要な著者: Shali Shao (著者), Xibing Zhuang (著者), Lin Zhang (著者), Tiankui Qiao (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Fluoxetine, one of the latest clinical antidepressants, is reported to have the anti-proliferative effect on cancer cells via immune-related pathways. However, the mechanism is still not known. This study mainly focused on the discovery of the molecular basis of the inhibitory effect of fluoxetine i...