Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients

• Những tác giả chính: Hoai‐Thu Thai (Tác giả), Kimiko Koiwai (Tác giả), Yoshihisa Shitara (Tác giả), Hirotaka Kazama (Tác giả), Jean‐Baptiste Fau (Tác giả), Dorothée Semiond (Tác giả), Christine Veyrat‐Follet (Tác giả)
• Định dạng: Sách
• Được phát hành: Wiley, 2023-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Abstract This study aimed to support dosing regimen selection for isatuximab as a single agent or in combination with dexamethasone for Japanese patients with relapsed/refractory multiple myeloma (RRMM). A joint model characterizing the dynamics of serum M‐protein kinetics and its association with p...