Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis

Abstract Juvenile primary fibromyalgia syndrome (JPFS) is a chronic, musculoskeletal pain syndrome affecting children and adolescents, most commonly adolescent girls. The syndrome has a multifactorial etiology, with altered central pain processing playing an important role. The hallmark symptom is s...

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Main Authors: Maya Levy Coles (Author), Rotem Weissmann (Author), Yosef Uziel (Author)
Format: Book
Published: BMC, 2021-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Maya Levy Coles  |e author 
700 1 0 |a Rotem Weissmann  |e author 
700 1 0 |a Yosef Uziel  |e author 
245 0 0 |a Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis 
260 |b BMC,   |c 2021-03-01T00:00:00Z. 
500 |a 10.1186/s12969-021-00493-6 
500 |a 1546-0096 
520 |a Abstract Juvenile primary fibromyalgia syndrome (JPFS) is a chronic, musculoskeletal pain syndrome affecting children and adolescents, most commonly adolescent girls. The syndrome has a multifactorial etiology, with altered central pain processing playing an important role. The hallmark symptom is severe, widespread musculoskeletal pain. Other symptoms include sleep and mood disturbances, headaches, stiffness, and subjective joint swelling. Physical examination can reveal multiple tender points. The diagnosis is clinical, with defined criteria. Early diagnosis and intervention are important. In this part of the review, we discuss the epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis of JPFS. Part two will focus on treatment and prognosis. 
546 |a EN 
690 |a Fibromyalgia 
690 |a Juvenile 
690 |a JPFS 
690 |a Chronic pain 
690 |a Musculoskeletal pain syndrome 
690 |a Pediatrics 
690 |a RJ1-570 
690 |a Diseases of the musculoskeletal system 
690 |a RC925-935 
655 7 |a article  |2 local 
786 0 |n Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-10 (2021) 
787 0 |n https://doi.org/10.1186/s12969-021-00493-6 
787 0 |n https://doaj.org/toc/1546-0096 
856 4 1 |u https://doaj.org/article/daaae4be04c34f0a89a698ab19f3066a  |z Connect to this object online.