Chronic hypoxia impairs skeletal muscle repair via HIF‐2α stabilization

• Main Authors: Amelia Yin (Author), Wenyan Fu (Author), Anthony Elengickal (Author), Joonhee Kim (Author), Yang Liu (Author), Anne Bigot (Author), Kamal Mamchaoui (Author), Jarrod A. Call (Author), Hang Yin (Author)
• Format: Book
• Published: Wiley, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chronic hypoxia and skeletal muscle atrophy commonly coexist in patients with COPD and CHF, yet the underlying physio‐pathological mechanisms remain elusive. Muscle regeneration, driven by muscle stem cells (MuSCs), holds therapeutic potential for mitigating muscle atrophy. This...