Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway

• Główni autorzy: Sakiko Nishikawa (Autor), Yasumichi Inoue (Autor), Yuka Hori (Autor), Chiharu Miyajima (Autor), Daisuke Morishita (Autor), Nobumichi Ohoka (Autor), Shigeaki Hida (Autor), Toshiaki Makino (Autor), Hidetoshi Hayashi (Autor)
• Format: Książka
• Wydane: MDPI AG, 2020-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Kurarinone, a flavonoid isolated from the roots of <i>Sophora flavescens</i>, was suggested to exert potent antioxidant and immunosuppressive effects. However, the underlying mechanisms remain unclear. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor that...