REverSe TRanscrIptase chain termination (RESTRICT) for selective measurement of nucleotide analogs used in HIV care and prevention

• Main Authors: Ayokunle O. Olanrewaju (Author), Benjamin P. Sullivan (Author), Alicia H. Gim (Author), Cosette A. Craig (Author), Derin Sevenler (Author), Andrew T. Bender (Author), Paul K. Drain (Author), Jonathan D. Posner (Author)
• Format: Book
• Published: Wiley, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Sufficient drug concentrations are required for efficacy of antiretroviral drugs used in HIV care and prevention. Measurement of nucleotide analogs, included in most HIV medication regimens, enables monitoring of short‐ and long‐term adherence and the risk of treatment failure. The REverSe...