The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency
The protein tyrosine phosphatase PTP1B is a negative regulator of both insulin and leptin signaling and is involved in the control of glucose homeostasis and energy expenditure. Due to its prominent role in regulating metabolism, PTP1B is a promising therapeutic target for the treatment of human obe...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2012-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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