Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series

There has been a recent surge in adenoviral infections with poor outcomes. This case series describes the clinical profile and outcome of 38 children admitted with adenovirus infection with severe acute respiratory illness (SARI). The majority (68.4%) were infants, 25 (65.7%) were immunocompetent, a...

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Bibliographic Details
Main Authors: Rajarshi Bera (Author), Pallavi Pallavi (Author), Sonal Saxena (Author), Shashi Chawla (Author), Urmila Jhamb (Author), Romit Saxena (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2024-09-01T00:00:00Z.
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Summary:There has been a recent surge in adenoviral infections with poor outcomes. This case series describes the clinical profile and outcome of 38 children admitted with adenovirus infection with severe acute respiratory illness (SARI). The majority (68.4%) were infants, 25 (65.7%) were immunocompetent, and 13 (34.2%) had an underlying comorbidity. Twenty-seven (71%) patients required mechanical ventilation and 5 (13.1%) were managed on a heated high-flow nasal cannula. Nine (23.6%) children developed acute respiratory distress syndrome and four (10.5%) cases developed postinfectious bronchiolitis obliterans (PIBO). The median duration of mechanical ventilation was 24 days interquartile range [11.5-34.5] days. Eleven (28.9%) children in the study population expired.
Item Description:2349-6592
2455-7099
10.4103/jpcc.jpcc_46_24