Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1-40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus

• Principais autores: Yue Tian (Autor), Ke-yan Chen (Autor), Li-dan Liu (Autor), Yun-xia Dong (Autor), Ping Zhao (Autor), Shan-bin Guo (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2018-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objective. This study was aimed at investigating whether sevoflurane inhalation induced cognitive impairment in rats with a possible mechanism involved in the event. Methods. Thirty-two rats were randomly divided into four groups of normal saline (NS) + O2, NS + sevoflurane (sevo), amyloid-β peptide...