Viscosupplementation with Hyaluronic acid as an Adjuvant to Diacerein in improving Pain, Stiffness and Physical function in Primary Osteoarthritic Knees: a 1 year follow-up observation study

• Main Authors: Deo Rishi Tripathi (Author), Mahesh Kumar Talele (Author), Amod Kumar (Author), Harleen Uppal (Author), Deepak Kumar (Author)
• Format: Book
• Published: Al Ameen Medical College, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In the arthritic joint, the concentration and molecular weight of hyaluronic acid are decreased by 33% to 50% because the synthesis of hyaluronic acid in OA is disrupted by increased levels of pro-inflammatory cytokines, free radicals and proteinases. The American College of Rheumatology...