Current role of community-acquired methicillin-resistant Staphylococcus aureus among children with skin and soft tissue infections

• Main Authors: Carlos G. Teran (Author), Sunitha Sura (Author), Tarek Mohamed (Author), Thant Lin (Author), Marsha Medows (Author), Donkor Cynthia (Author), Sze H. Wong (Author)
• Format: Book
• Published: MDPI AG, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Community-acquired methicillin-resistant Staphylococcus aureus has become a wellestablished pathogen with alarming rates during the last decade. The current situation of this bacteria in pediatric infections is very limited and motivated us to conduct this study. This is a retrospective and analytical study including patients less than 18 years of age with the diagnosis of skin or soft tissue infections in 2008 and 2009 meeting the criteria of Community-acquired infection. A prevalence of 41.9% among skin and soft tissue infections was found. Inducible resistance to clindamycin was detected in 1.3% of the strains and the infection shows a seasonal predilection for summer (P=0.003); 57.8% of the cases required hospitalization with a mean stay of 3.3±2.5 days. The susceptibility to clindamycin and co-trimoxazole is 88 and 97% respectively. The resistance to erythromycin has reached 92%. The main diagnoses at presentation was gluteal abscess plus cellulitis (34.2%). The prevalence of CA-MRSA is trending up and seems to become a large burden for the health system in our community. Clindamycin is still an excellent option in the community setting since inducible clindamycin resistance is extremely low in this community. Co-trimoxazole should be kept as a reserved drug to avoid the rapid resurgence resistance in the community.

Item Description

2036-749X
2036-7503
10.4081/pr.2012.e5