Dupilumab-associated sezary syndrome

Dupilumab is a monoclonal antibody that inhibits interleukin-4 (IL-4) and interleukin-13 (IL-13), approved for the treatment of adults with moderate-to-severe atopic dermatitis (AD). While recent reports have described cases of new-onset mycosis fungoides (MF) following treatment with dupilumab for...

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Bibliographic Details
Main Authors: Austin Hamp (Author), Jamie Hanson (Author), Albert Alhatem (Author), Robert A Schwartz (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2023-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Austin Hamp  |e author 
700 1 0 |a Jamie Hanson  |e author 
700 1 0 |a Albert Alhatem  |e author 
700 1 0 |a Robert A Schwartz  |e author 
245 0 0 |a Dupilumab-associated sezary syndrome 
260 |b Wolters Kluwer Medknow Publications,   |c 2023-01-01T00:00:00Z. 
500 |a 0019-5154 
500 |a 1998-3611 
500 |a 10.4103/ijd.ijd_580_22 
520 |a Dupilumab is a monoclonal antibody that inhibits interleukin-4 (IL-4) and interleukin-13 (IL-13), approved for the treatment of adults with moderate-to-severe atopic dermatitis (AD). While recent reports have described cases of new-onset mycosis fungoides (MF) following treatment with dupilumab for AD, to our knowledge only one patient has been delineated with the progression to SS. We present an additional case of a patient who was diagnosed with SS following treatment with dupilumab for adult-onset AD and asthma. We examine SS as a possible side effect of dupilumab while also discussing management and theories to explain this phenomenon. 
546 |a EN 
690 |a atopic dermatitis 
690 |a dupilumab 
690 |a mycosis fungoides 
690 |a sézary syndrome 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Indian Journal of Dermatology, Vol 68, Iss 4, Pp 459-462 (2023) 
787 0 |n http://www.e-ijd.org/article.asp?issn=0019-5154;year=2023;volume=68;issue=4;spage=459;epage=462;aulast=Hamp 
787 0 |n https://doaj.org/toc/0019-5154 
787 0 |n https://doaj.org/toc/1998-3611 
856 4 1 |u https://doaj.org/article/dc48e905d48747a49b4076bca6fdcbf6  |z Connect to this object online.