L-type voltage-gated calcium channel agonists mitigate hearing loss and modify ribbon synapse morphology in the zebrafish model of Usher syndrome type 1
The mariner (myo7aa−/−) mutant is a zebrafish model for Usher syndrome type 1 (USH1). To further characterize hair cell synaptic elements in myo7aa−/− mutants, we focused on the ribbon synapse and evaluated ultrastructure, number and distribution of immunolabeled ribbons, and postsynaptic densities....
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Main Authors: | Alaa Koleilat (Author), Joseph A. Dugdale (Author), Trace A. Christenson (Author), Jeffrey L. Bellah (Author), Aaron M. Lambert (Author), Mark A. Masino (Author), Stephen C. Ekker (Author), Lisa A. Schimmenti (Author) |
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Format: | Book |
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The Company of Biologists,
2020-11-01T00:00:00Z.
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