Pan-Genome Plasticity and Virulence Factors: A Natural Treasure Trove for <i>Acinetobacter baumannii</i>
<i>Acinetobacter baumannii</i> is a Gram-negative pathogen responsible for a variety of community- and hospital-acquired infections. It is recognized as a life-threatening pathogen among hospitalized individuals and, in particular, immunocompromised patients in many countries. <i>A...
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2024-03-01T00:00:00Z.
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| Summary: | <i>Acinetobacter baumannii</i> is a Gram-negative pathogen responsible for a variety of community- and hospital-acquired infections. It is recognized as a life-threatening pathogen among hospitalized individuals and, in particular, immunocompromised patients in many countries. <i>A. baumannii,</i> as a member of the ESKAPE group, encompasses high genomic plasticity and simultaneously is predisposed to receive and exchange the mobile genetic elements (MGEs) through horizontal genetic transfer (HGT). Indeed, <i>A. baumannii</i> is a treasure trove that contains a high number of virulence factors. In accordance with these unique pathogenic characteristics of <i>A. baumannii</i>, the authors aim to discuss the natural treasure trove of pan-genome and virulence factors pertaining to this bacterial monster and try to highlight the reasons why this bacterium is a great concern in the global public health system. |
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| Item Description: | 10.3390/antibiotics13030257 2079-6382 |