Pharmacokinetic Characterization of Supinoxin and Its Physiologically Based Pharmacokinetic Modeling in Rats
Supinoxin is a novel anticancer drug candidate targeting the Y593 phospho-p68 RNA helicase, by exhibiting antiproliferative activity and/or suppression of tumor growth. This study aimed to characterize the in vitro and in vivo pharmacokinetics of supinoxin and attempt physiologically based pharmacok...
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Main Authors: | Yoo-Kyung Song (Author), Yun-Hwan Seol (Author), Min Ju Kim (Author), Jong-Woo Jeong (Author), Hae-In Choi (Author), Seung-Won Lee (Author), Yoon-Jee Chae (Author), Sunjoo Ahn (Author), Young-Dae Gong (Author), Kyeong-Ryoon Lee (Author), Tae-Sung Koo (Author) |
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Format: | Book |
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MDPI AG,
2021-03-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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