Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway

• Main Authors: Ming Xiang (Author), Tingting Liu (Author), Cheng Tian (Author), Kun Ma (Author), Jing Gou (Author), Rongrong Huang (Author), Senlin Li (Author), Qing Li (Author), Chuanrui Xu (Author), Lei Li (Author), Chih-Hao Lee (Author), Yonghui Zhang (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Kinsenoside (KD) exhibits anti-inflammatory and immunosuppressive effects. Dendritic cells (DCs) are critical regulators of the pathologic inflammatory milieu in liver fibrosis (LF). Herein, we explored whether and how KD repressed development of LF via DC regulation and verified the pathway involve...