Accelerated sarcopenia precedes learning and memory impairments in the P301S mouse model of tauopathies and Alzheimer's disease
Abstract Background Alzheimer's disease (AD) impairs cognitive functions and peripheral systems, including skeletal muscles. The PS19 mouse, expressing the human tau P301S mutation, shows cognitive and muscular pathologies, reflecting the central and peripheral atrophy seen in AD. Methods We an...
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Main Authors: | Savannah Longo (Author), María Laura Messi (Author), Zhong‐Min Wang (Author), William Meeker (Author), Osvaldo Delbono (Author) |
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Format: | Book |
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Wiley,
2024-08-01T00:00:00Z.
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