Herbal Transformation by Fermentation
We herein show a dramatic change of herbal properties of the composition as well as function via fermentation of Cynanchi atrati Radix (family Asclepiadaceae). Cynanchi atrati Radix showed a high cytotoxicity against B16-F10 melanoma cell line, but the function of Cynanchi atrati Radix was completel...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Medical Association of Pharmacopuncture Institute,
2020-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | We herein show a dramatic change of herbal properties of the composition as well as function via fermentation of Cynanchi atrati Radix (family Asclepiadaceae). Cynanchi atrati Radix showed a high cytotoxicity against B16-F10 melanoma cell line, but the function of Cynanchi atrati Radix was completely changed into anti-melanin activity at very low concentration after Lactobacillus -fermentation. In addition, the compounds were drastically changed as shown in HPLC-based profile. Furthermore, this transformation has been achieved by only Lactobacillus -fermentation. This study proposes an strategy which we need to consider in the herb-derived material researches including pharmacopuncture. |
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| Item Description: | 2005-2901 10.1016/j.jams.2020.10.001 |