Peripheral combination treatment of leptin and an SGLT2 inhibitor improved glucose metabolism in insulin-dependent diabetes mellitus mice

• मुख्य लेखकों: Hiroshi Yaginuma (लेखक), Ryoichi Banno (लेखक), Runan Sun (लेखक), Keigo Taki (लेखक), Akira Mizoguchi (लेखक), Tomoko Kobayashi (लेखक), Mariko Sugiyama (लेखक), Taku Tsunekawa (लेखक), Takeshi Onoue (लेखक), Hiroshi Takagi (लेखक), Daisuke Hagiwara (लेखक), Yoshihiro Ito (लेखक), Shintaro Iwama (लेखक), Hidetaka Suga (लेखक), Hiroshi Arima (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We investigated whether peripheral combination treatment of a sodium-glucose cotransporter 2 (SGLT2) inhibitor and leptin improves glucose metabolism in insulin-dependent diabetes mellitus (IDDM) model mice. Twelve-week-old male C57BL6 mice were intraperitoneally administered a high dose of streptoz...