DoE-Based Design of a Simple but Efficient Preparation Method for a Non-Effervescent Gastro-Retentive Floating Tablet Containing Metformin HCl

• 主要な著者: Byungsuk Kim (著者), Youngjoo Byun (著者), Eun Hee Lee (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

A sustained-release non-effervescent floating matrix tablet was prepared using a simple and efficient direct compression of spray-dried granules containing metformin hydrochloride and cetyl alcohol with hydroxypropyl methylcellulose K15M (HPMC K15M). The design of experiments was employed to explore...