Roles of dental pulp fibroblasts in the recognition of bacterium-related factors and subsequent development of pulpitis

• Main Authors: Tadashi Nakanishi (Author), Daisuke Takegawa (Author), Kouji Hirao (Author), Kanako Takahashi (Author), Hiromichi Yumoto (Author), Takashi Matsuo (Author)
• Format: Book
• Published: Elsevier, 2011-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As caries-related bacteria invade deeply into dentin and come into close proximity to the pulp, inflammatory cells (such as lymphocytes, macrophages and neutrophils) infiltrate into the bacterium-invaded area and consequently pulpitis develops. Many types of cytokines and adhesion molecules are resp...