Evaluation of the Wound Healing Potential of Some Natural Polymers on Three Experimental Models
The aim of this paper was the preparation and investigation of the wound healing properties of four topical formulations based on natural polymers such as collagen, chitosan, lyophilized egg white, and a mixture of them. The therapeutic assessment of these four ointments was carried out in vivo on t...
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MDPI AG,
2021-05-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_ddf29f15996846fbb50be1b6d1c8e84e | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Calin Vasile Andritoiu |e author |
| 700 | 1 | 0 | |a Corina Elena Andriescu |e author |
| 700 | 1 | 0 | |a Maricel Danu |e author |
| 700 | 1 | 0 | |a Cristina Lungu |e author |
| 700 | 1 | 0 | |a Bianca Ivanescu |e author |
| 700 | 1 | 0 | |a Cornel Havarneanu |e author |
| 700 | 1 | 0 | |a Marcel Popa |e author |
| 245 | 0 | 0 | |a Evaluation of the Wound Healing Potential of Some Natural Polymers on Three Experimental Models |
| 260 | |b MDPI AG, |c 2021-05-01T00:00:00Z. | ||
| 500 | |a 10.3390/ph14050465 | ||
| 500 | |a 1424-8247 | ||
| 520 | |a The aim of this paper was the preparation and investigation of the wound healing properties of four topical formulations based on natural polymers such as collagen, chitosan, lyophilized egg white, and a mixture of them. The therapeutic assessment of these four ointments was carried out in vivo on the incision, excision, and thermal burn wounds induced on Wistar rats. The treatment was applied topically on wounds once a day, for 21 days. The experimental results were analyzed from a clinical and histopathological point of view. The rheological characterization of the topical formulations was also performed in order to verify their spreadability and structural stability. All ointments had a positive effect on wound contraction and re-epithelization processes, but the one based on total polymers had a significant healing potential on the designed cutaneous lesions due to its synergistic effects. | ||
| 546 | |a EN | ||
| 690 | |a natural polymers | ||
| 690 | |a chitosan | ||
| 690 | |a collagen | ||
| 690 | |a ovalbumin | ||
| 690 | |a egg white | ||
| 690 | |a wound healing | ||
| 690 | |a Medicine | ||
| 690 | |a R | ||
| 690 | |a Pharmacy and materia medica | ||
| 690 | |a RS1-441 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Pharmaceuticals, Vol 14, Iss 5, p 465 (2021) | |
| 787 | 0 | |n https://www.mdpi.com/1424-8247/14/5/465 | |
| 787 | 0 | |n https://doaj.org/toc/1424-8247 | |
| 856 | 4 | 1 | |u https://doaj.org/article/ddf29f15996846fbb50be1b6d1c8e84e |z Connect to this object online. |