MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations

• Hoofdauteurs: Ryan N. Doan (Auteur), Michael B. Miller (Auteur), Sonia N. Kim (Auteur), Rachel E. Rodin (Auteur), Javier Ganz (Auteur), Sara Bizzotto (Auteur), Katherine S. Morillo (Auteur), August Yue Huang (Auteur), Reethika Digumarthy (Auteur), Zachary Zemmel (Auteur), Christopher A. Walsh (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2021-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Mosaic mutations contribute to numerous human disorders. As such, the identification and precise quantification of mosaic mutations is essential for a wide range of research applications, clinical diagnoses, and early detection of cancers. Currently, the low-throughput nature of...