Fine particulate matter aggravates smoking induced lung injury via NLRP3/caspase-1 pathway in COPD

• Main Authors: Chiwook Chung (Author), Suk Young Park (Author), Jin-Young Huh (Author), Na Hyun Kim (Author), ChangHo Shon (Author), Eun Yi Oh (Author), Young-Jun Park (Author), Seon-Jin Lee (Author), Hwan-Cheol Kim (Author), Sei Won Lee (Author)
• Format: Book
• Published: BMC, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Exposure to noxious particles, including cigarette smoke and fine particulate matter (PM2.5), is a risk factor for chronic obstructive pulmonary disease (COPD) and promotes inflammation and cell death in the lungs. We investigated the combined effects of cigarette smoking and PM2...