Azelastine and suplatast shorten the distribution half-life of IgE in rats

• Main Authors: Kazuhiko Hanashiro (Author), Yoshihiro Tokeshi (Author), Toshiyuki Nakasone (Author), Masanori Sunagawa (Author), Mariko Nakamura (Author), Tadayoshi Kosugi (Author)
• Format: Book
• Published: Hindawi Limited, 2002-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We aim to clarify whether suplatast and azelastine (anti-allergic drugs) can shorten the half-life of immunoglobulin E (IgE) in the circulating blood. Thirty Wistar rats were divided into six groups. Distilled water or anti-allergic drugs were given orally for 6 days after the first sensitization. T...