N-Chromosome Royal Jelly, Propolis and Bee Pollen Supplementation Improve the Clinical Conditions of COVID-19 Patients: A Randomized Controlled Trial

• Main Authors: Atefeh Abedini (Author), Shadi Shafaghi (Author), Zahra Ameri Ahmad (Author), Elmira Javanmardi (Author), Fariba Ghorbani (Author), Babak Sharif-Kashani (Author), Farah Naghashzadeh (Author), Masoud Shafaghi (Author), Melina Moshirpour (Author), Sima Noorali (Author), Hoda Hakimian (Author), Mohammad Sadegh Keshmiri (Author), Aylar Fazlzadeh (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Royal jelly, propolis, and bee pollen are used for different purposes all around the world according to their anti-inflammatory, antioxidant, and antimicrobial activities. Given that Coronavirus 2019 (COVID-19) is a viral condition accompanied by a dysregulated inflammatory response in the body, we intend to evaluate the effects of natural supplementations on the disease course. A randomized, open-label, controlled trial was conducted among 50 definitive cases of COVID-19. These patients were randomly assigned into control and intervention groups. Royal Jelly, propolis, and bee pollen were prescribed to patients in the intervention group (n = 24) in addition to conventional treatment; while the control group only received the standard treatment (n = 26). At the end of the study, functional class improved in both groups, but this change was more pronounced in the intervention group (p < 0.05). Moreover, total symptoms duration and the time to return to work were significantly reduced in the intervention group (p < 0.05). Although royal jelly, propolis, and bee pollen are not definitive treatments in COVID-19 patients, they can be used as an adjuvant treatment to limit disease symptoms and virus propagation.

Item Description

10.18502/tim.v6i4.8269
2476-5104
2476-5112