Pulmonary Exacerbation of Undiagnosed Toxocariasis in Intensively-Treated High-Risk Neuroblastoma Patients

Toxocariasis is one of the most common zoonoses, with high seroprevalence in apparently healthy individuals. Neuroblastoma is an aggressive childhood cancer. The cure rates are improving due to dose-dense chemotherapy, progress in surgical practice, myeloablative therapy with autologous stem cell tr...

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Main Authors: Szymon Janczar (Author), Monika Bulas (Author), Justyna Walenciak (Author), Dobromila Baranska (Author), Marek Ussowicz (Author), Wojciech Młynarski (Author), Beata Zalewska-Szewczyk (Author)
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Published: MDPI AG, 2020-10-01T00:00:00Z.
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001 doaj_decdc3eddfa94eecb0ceac103e5b077e
042 |a dc 
100 1 0 |a Szymon Janczar  |e author 
700 1 0 |a Monika Bulas  |e author 
700 1 0 |a Justyna Walenciak  |e author 
700 1 0 |a Dobromila Baranska  |e author 
700 1 0 |a Marek Ussowicz  |e author 
700 1 0 |a Wojciech Młynarski  |e author 
700 1 0 |a Beata Zalewska-Szewczyk  |e author 
245 0 0 |a Pulmonary Exacerbation of Undiagnosed Toxocariasis in Intensively-Treated High-Risk Neuroblastoma Patients 
260 |b MDPI AG,   |c 2020-10-01T00:00:00Z. 
500 |a 10.3390/children7100169 
500 |a 2227-9067 
520 |a Toxocariasis is one of the most common zoonoses, with high seroprevalence in apparently healthy individuals. Neuroblastoma is an aggressive childhood cancer. The cure rates are improving due to dose-dense chemotherapy, progress in surgical practice, myeloablative therapy with autologous stem cell transplantation, and recently, anti-GD2 immunotherapy. This is associated with a burden of complications, some of which are relatively specific for neuroblastoma treatment. Based on previous reports of <i>Toxocara canis</i> infection in high-risk neuroblastoma patients and cases of pulmonary exacerbation from our center in this disease, we propose that toxocariasis is a specific complication of intensive pediatric cancer treatment and advocate for active surveillance. 
546 |a EN 
690 |a neuroblastoma 
690 |a toxocariasis 
690 |a autologous stem cell transplantation 
690 |a Toxocara 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Children, Vol 7, Iss 10, p 169 (2020) 
787 0 |n https://www.mdpi.com/2227-9067/7/10/169 
787 0 |n https://doaj.org/toc/2227-9067 
856 4 1 |u https://doaj.org/article/decdc3eddfa94eecb0ceac103e5b077e  |z Connect to this object online.