Role of targeted therapy in the treatment of HER-2-positive breast cancer brain metastases

• Main Authors: G. A. Dashyan (Author), V. F. Semiglazov (Author), P. V. Krivorot'ko (Author), T. Yu. Semiglazova (Author), E. E. Topuzov (Author), R. M. Paltuev (Author), K. Yu. Zernov (Author), V. S. Apollonova (Author), S. S. Ereshchenko (Author), A. V. Petrova (Author), E. K. Zhil'tsova (Author), O. A. Ivanova (Author)
• Format: Book
• Published: ABV-press, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brain metastases are detectable in 25-35 % of patients with progressive HER-2-positve breast cancer. Even after spreading metastases into the brain, chemotherapy in combination with anti-HER- 2 therapy improves survival due to better control of the systemic disease. The paper presents the results of...