Phenotypic and functional characterization of Bst+/− mouse retina

• Main Authors: Hamidreza Riazifar (Author), Guoli Sun (Author), Xinjian Wang (Author), Alan Rupp (Author), Shruti Vemaraju (Author), Fred N. Ross-Cisneros (Author), Richard A. Lang (Author), Alfredo A. Sadun (Author), Samer Hattar (Author), Min-Xin Guan (Author), Taosheng Huang (Author)
• Format: Book
• Published: The Company of Biologists, 2015-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The belly spot and tail (Bst+/−) mouse phenotype is caused by mutations of the ribosomal protein L24 (Rpl24). Among various phenotypes in Bst+/− mice, the most interesting are its retinal abnormalities, consisting of delayed closure of choroid fissures, decreased ganglion cells and subretinal vascul...