Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance

Objective: To determine whether pharmacist is able to guaranteecold chain maintenance of thermolabile drugs during transportusing the available information in the reception processand to compare these results with those obtained in a subsequentintervention phase, in which the manufacturing laborator...

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Main Authors: I. Ricote-Lobera (Author), B. Santos-Mena (Author), S. Fraile-Gil (Author), B. Ortiz-Martín (Author), F. J. Hidalgo-Correas (Author), B. García-Díaz (Author)
Format: Book
Published: Elsevier, 2014-05-01T00:00:00Z.
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042 |a dc 
100 1 0 |a I. Ricote-Lobera  |e author 
700 1 0 |a B. Santos-Mena  |e author 
700 1 0 |a S. Fraile-Gil  |e author 
700 1 0 |a B. Ortiz-Martín  |e author 
700 1 0 |a F. J. Hidalgo-Correas  |e author 
700 1 0 |a B. García-Díaz  |e author 
245 0 0 |a Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance 
260 |b Elsevier,   |c 2014-05-01T00:00:00Z. 
500 |a 10.7399/fh.2014.38.3.1123 
500 |a 1130-6343 
500 |a 2171-8695 
520 |a Objective: To determine whether pharmacist is able to guaranteecold chain maintenance of thermolabile drugs during transportusing the available information in the reception processand to compare these results with those obtained in a subsequentintervention phase, in which the manufacturing laboratorieswere contacted. Methods: Intervention study, prospective and comparative"before-after". It was analyzed the storage conditions duringtransport of all thermolabile drugs received in a 400-bed hospitalfor 3 months, excluding those from clinical trials. Results: The intervention allowed to ensure cold chain maintenancein 76,5% (n = 488) of received drugs, representing anincrease of 41,8% (IC 95% 36,7-46,6%; p < 0,001) comparedwith the percentage obtained before the intervention. Conclusions: The pharmacist isn't able to ensure the cold chainmaintenance of received thermolabile drugs without temperaturemonitoring device (64,6%). Reports requested from laboratoriesallowed to increase significantly that percentage. 
546 |a EN 
546 |a ES 
690 |a Cold chain 
690 |a Thermolabile drugs; 
690 |a Drug stability 
690 |a Drug distribution 
690 |a Refrigeration 
690 |a Pharmacist intervention 
690 |a Protocol 
690 |a ; Quality 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Farmacia Hospitalaria, Vol 38, Iss 3, Pp 211-215 (2014) 
787 0 |n http://www.aulamedica.es/fh/pdf/1123.pdf 
787 0 |n https://doaj.org/toc/1130-6343 
787 0 |n https://doaj.org/toc/2171-8695 
856 4 1 |u https://doaj.org/article/df4c8823e40e4d1e8072cbb13f4458c9  |z Connect to this object online.