Effect of an herb root extract, herbal dentifrice and synthetic dentifrice on human salivary amylase

Background: Salivary amylase is an enzyme, which plays a vital role in formation of dental plaque. It has the ability to bind on the bacterial surfaces and to hydrolyze starch, giving rise to products that are transformed into acids leading to dental caries. Suppression of salivary amylase activity...

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Bibliographic Details
Main Authors: Gaurav Sapra (Author), Yogesh Kumar Vyas (Author), Rahul Agarwal (Author), Ashish Aggarwal (Author), K T Chandrashekar (Author), Kanika Sharma (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Gaurav Sapra  |e author 
700 1 0 |a Yogesh Kumar Vyas  |e author 
700 1 0 |a Rahul Agarwal  |e author 
700 1 0 |a Ashish Aggarwal  |e author 
700 1 0 |a K T Chandrashekar  |e author 
700 1 0 |a Kanika Sharma  |e author 
245 0 0 |a Effect of an herb root extract, herbal dentifrice and synthetic dentifrice on human salivary amylase 
260 |b Wolters Kluwer Medknow Publications,   |c 2013-01-01T00:00:00Z. 
500 |a 1735-3327 
500 |a 2008-0255 
500 |a 10.4103/1735-3327.118469 
520 |a Background: Salivary amylase is an enzyme, which plays a vital role in formation of dental plaque. It has the ability to bind on the bacterial surfaces and to hydrolyze starch, giving rise to products that are transformed into acids leading to dental caries. Suppression of salivary amylase activity can lead to decrease in risk of dental caries and plaque associated periodontal diseases. The aim of this study was to evaluate the effect of an herb, Spilanthes calva (in form of a test dentifrice) on human salivary amylase activity and to compare it with other dentifrices. Materials and Methods: A total of 80 subjects of age 18-35 years were randomly selected and divided equally into 4 groups. Group 1 subjects were assigned to use Test Dentifrice (with S. calva root extract), while Group 2, Group 3, and Group 4 subjects were assigned to use Herbal Dentifrice (Arodent™ ), Synthetic Dentifrice (Colgate ® ), and Control Dentifrice respectively. Salivary amylase activity was determined by Bernfeld method in each group, before and after using the given dentifrices. Results: Maximum inhibition of salivary amylase activity was found in the group using test dentifrice as compared to others. Conclusion: The present study indicates that, the root extract of S. calva possess significant inhibitory activity for salivary amylase. Use of S. calva root extract will provide a wider protection against different pathogenic oral microflora. Use of this extract singly or in combination is strongly recommended in the dentifrice formulations. 
546 |a EN 
690 |a Dental caries 
690 |a dental plaque 
690 |a dentifrice 
690 |a Spilanthes calva 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Dental Research Journal, Vol 10, Iss 4, Pp 493-498 (2013) 
787 0 |n http://www.drjjournal.net/article.asp?issn=1735-3327;year=2013;volume=10;issue=4;spage=493;epage=498;aulast=Sapra 
787 0 |n https://doaj.org/toc/1735-3327 
787 0 |n https://doaj.org/toc/2008-0255 
856 4 1 |u https://doaj.org/article/df67fb5f662e4ae0a89b9e69dba1a0e1  |z Connect to this object online.