Cross-species/cross-modality physiologically based pharmacokinetics for biologics: 89Zr-labelled albumin-binding domain antibody GSK3128349 in humans

Two-pore physiologically-based pharmacokinetics (PBPK) for biologics describes the tissue distribution and elimination kinetics of soluble proteins as a function of their hydrodynamic radius and the physiological properties of the organs. Whilst many studies have been performed in rodents to paramet...

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Bibliographic Details
Main Authors: Armin Sepp (Author), Mats Bergström (Author), Marie Davies (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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