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Bi-Functional Alginate Oligosaccharide-Polymyxin Conjugates for Improved Treatment of Multidrug-Resistant Gram-Negative Bacterial Infections

The recent emergence of resistance to colistin, an antibiotic of last resort with dose-limiting toxicity, has highlighted the need for alternative approaches to combat infection. This study aimed to generate and characterise alginate oligosaccharide ("OligoG")-polymyxin (polymyxin B and E...

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Main Authors: Joana Stokniene (Author), Lydia C. Powell (Author), Olav A. Aarstad (Author), Finn L. Aachmann (Author), Philip D. Rye (Author), Katja E. Hill (Author), David W. Thomas (Author), Elaine L. Ferguson (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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