Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies.

• Main Authors: Stephanie J Migchelsen (Author), Diana L Martin (Author), Khamphoua Southisombath (Author), Patrick Turyaguma (Author), Anne Heggen (Author), Peter Paul Rubangakene (Author), Hassan Joof (Author), Pateh Makalo (Author), Gretchen Cooley (Author), Sarah Gwyn (Author), Anthony W Solomon (Author), Martin J Holland (Author), Paul Courtright (Author), Rebecca Willis (Author), Neal D E Alexander (Author), David C W Mabey (Author), Chrissy H Roberts (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Efforts are underway to eliminate trachoma as a public health problem by 2020. Programmatic guidelines are based on clinical signs that correlate poorly with Chlamydia trachomatis (Ct) infection in post-treatment and low-endemicity settings. Age-specific seroprevalence of anti Ct Pgp3 ant...