The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors

P2X receptors are trimeric eukaryotic ATP-gated cation channels. Extracellular ATP-their physiological ligand-is released as a neurotransmitter and in conditions of cell damage such as inflammation, and substantial evidence implicates P2X receptors in diseases including neuropathic pain, cancer, and...

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Main Authors: Gaia Pasqualetto (Author), Andrea Brancale (Author), Mark T. Young (Author)
Format: Book
Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
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