Altered Hepatic Lipid Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice
Nonalcoholic fatty liver disease (NAFLD) is strongly linked to obesity, insulin resistance, and abnormal hepatic lipid metabolism; however, the precise regulation of these processes remains poorly understood. Here we examined genes and proteins involved in hepatic oxidation and lipogenesis in 14-wee...
Saved in:
Main Authors: | James W. Perfield (Author), Laura C. Ortinau (Author), R. Taylor Pickering (Author), Meghan L. Ruebel (Author), Grace M. Meers (Author), R. Scott Rector (Author) |
---|---|
Format: | Book |
Published: |
Hindawi Limited,
2013-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of leptin on in vitro maturation, fertilization and embryonic cleavage after ICSI and early developmental expression of leptin (Ob) and leptin receptor (ObR) proteins in the horse
by: Arrighi Silvana, et al.
Published: (2009) -
Leptin Administration Downregulates the Increased Expression Levels of Genes Related to Oxidative Stress and Inflammation in the Skeletal Muscle of ob/ob Mice
by: Neira Sáinz, et al.
Published: (2010) -
Choline Deficiency Attenuates Body Weight Gain and Improves Glucose Tolerance in ob/ob Mice
by: Gengshu Wu, et al.
Published: (2012) -
Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lepob/ob mice
by: Anna M. D'souza, et al.
Published: (2016) -
Beneficial Effect of Genistein on Diabetes-Induced Brain Damage in the ob/ob Mouse Model
by: Li R, et al.
Published: (2020)