Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: A randomized clinical trial

• Main Authors: Zahra Sahraei (Author), Ali Saffaei (Author), Ilad Alavi Darazam (Author), Jamshid Salamzadeh (Author), Minoosh Shabani (Author), Shervin Shokouhi (Author), Najmeh Sarvmeili (Author), Mohammadreza Hajiesmaeili (Author), Masood Zangi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Vancomycin is a narrow therapeutic window glycopeptide antibiotic that acts against Gram-positive bacteria. As it is renally eliminated, therapeutic drug monitoring is recommended for vancomycin, especially in case of kidney function alteration. Augmented renal clearance (ARC), defined as a...