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Molecular Insight into <em>Mycobacterium tuberculosis</em> Resistance to Nitrofuranyl Amides Gained through Metagenomics-like Analysis of Spontaneous Mutants

We performed synthesis of new nitrofuranyl amides and investigated their anti-TB activity and primary genetic response of mycobacteria through whole-genome sequencing (WGS) of spontaneous resistant mutants. The in vitro activity was assessed on reference strain <i>Mycobacterium tuberculosis<...

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Príomhchruthaitheoirí:	Igor Mokrousov (Údar), Ivaylo Slavchev (Údar), Natalia Solovieva (Údar), Marine Dogonadze (Údar), Anna Vyazovaya (Údar), Violeta Valcheva (Údar), Aleksey Masharsky (Údar), Olesya Belopolskaya (Údar), Simeon Dimitrov (Údar), Viacheslav Zhuravlev (Údar), Isabel Portugal (Údar), João Perdigão (Údar), Georgi M. Dobrikov (Údar)
Formáid:	LEABHAR
Foilsithe / Cruthaithe:	MDPI AG, 2022-09-01T00:00:00Z.
Ábhair:	article
Rochtain ar líne:	Connect to this object online.
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!

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