Rifabutin Suppresses Inducible Clarithromycin Resistance in <i>Mycobacterium abscessus</i> by Blocking Induction of <i>whiB7</i> and <i>erm41</i>
Clarithromycin (CLR) is the corner stone in regimens for the treatment of lung disease caused by <i>Mycobacterium abscessus (Mab)</i>. However, many strains harbor the CLR-inducible CLR resistance gene <i>erm41,</i> encoding a ribosome methylase. Induction of <i>erm41&l...
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MDPI AG,
2020-02-01T00:00:00Z.
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