Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis

• Main Authors: Jinyun Zhao (Author), Yi Sun (Author), Xiaolong Sheng (Author), Jiaqi Xu (Author), Guoyu Dai (Author), Rundong He (Author), Yuxin Jin (Author), Zhide Liu (Author), Yong Xie (Author), Tianding Wu (Author), Yong Cao (Author), Jianzhong Hu (Author), Chunyue Duan (Author)
• Format: Book
• Published: BMC, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Lumbar facet joint osteoarthritis (LFJ OA) is a common disease, and there is still a lack of effective disease-modifying therapies. Our aim was to determine the therapeutic effect of hypoxia-treated adipose mesenchymal stem cell (ADSC)-derived exosomes (Hypo-ADSC-Exos) on the pro...