Schisandra chinensis Stem Ameliorates 3-Nitropropionic Acid-Induced Striatal Toxicity via Activation of the Nrf2 Pathway and Inhibition of the MAPKs and NF-κB Pathways

The beneficial value of the stems of Schisandra chinensis (SSC) in neurological diseases is unclear. We examined whether SSC aqueous extract (SSCE) alleviates striatal toxicity in a 3-nitropropionic acid (3-NPA)-induced mouse model of Huntington's disease (HD). SSCE (75, 150, or 300 mg/kg/day,...

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Main Authors: Eun-Jeong Kim (Author), Minhee Jang (Author), Min Jung Lee (Author), Jong Hee Choi (Author), Sung Joong Lee (Author), Sun Kwang Kim (Author), Dae Sik Jang (Author), Ik-Hyun Cho (Author)
Format: Book
Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
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