Gastric Tuberculosis Masquerading as Persistent Epigastric Pain in an Immunocompetent Patient: A Case Report

Tuberculosis (TB), caused by Mycobacterium tuberculosis , is a leading infectious disease with varied manifestations. We report a rare presentation of gastric TB in a 50-year-old immunocompetent woman from the Middle East with no prior medical history. The patient presented with persistent epigastri...

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Main Authors: Hasan Al-Obaidi MD (Author), Ahmed Dheyaa Al-Obaidi MBChB (Author), Pratiksha Moliya MD (Author), Hussein Harb MD (Author), Iya Agha MD (Author), Nooraldin Merza MD (Author), Hashim Talib Hashim MD (Author), Mustafa Najah Al-Obaidi MBChB (Author), Osamah Al-Obaidi FIBMS (Author)
Format: Book
Published: SAGE Publishing, 2024-11-01T00:00:00Z.
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Summary:Tuberculosis (TB), caused by Mycobacterium tuberculosis , is a leading infectious disease with varied manifestations. We report a rare presentation of gastric TB in a 50-year-old immunocompetent woman from the Middle East with no prior medical history. The patient presented with persistent epigastric pain, weight loss, nausea, and vomiting over a 2-month duration. Imaging studies and an infectious disease panel were inconclusive. However, upper endoscopy revealed a subepithelial lesion at the pylorus, with biopsies demonstrating caseating granuloma and multinucleated giant cells. A QuantiFERON test was subsequently positive for TB. The patient was successfully treated with standard TB quadruple therapy, resulting in significant improvement in symptoms during follow-up. This case underscores the importance of considering extrapulmonary TB in immunocompetent patients with atypical gastrointestinal symptoms and highlights the efficacy of prompt antitubercular therapy.
Item Description:2324-7096
10.1177/23247096241298160