Involvement of CD95 and ligand in CD4+ T-cell and CD8+ T-cell depletion and hepatic cytolysis in patients with chronic viral hepatitis B

• Main Authors: Franklin S. Azebaze Agueguia (Author), Paul Talla (Author), Marie C. Okomo Assoumou (Author), Graeme B. Jacobs (Author), Cedric H. Mbakam (Author), Elise Guiedem (Author), Martha Tongo Mesembe (Author), Emilia Lyonga (Author), George Mondinde Ikomey (Author)
• Format: Book
• Published: AOSIS, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Chronic viral hepatitis B (HBV) is characterised by progressive hepatocyte destruction and T-cell depletion. The mechanisms of the CD95-CD95 ligand (CD95L) signalling pathway during this chronic disease and the cirrhotic process remains unclear. Objective: We evaluated the involvement of...