Ascending Midbrain Dopaminergic Axons Require Descending GAD65 Axon Fascicles for Normal Pathfinding

• Main Authors: Claudia Marcela Garcia-Peña (Author), Minkyung eKim (Author), Daniela eFrade (Author), Daniela eAvila-Gonzalez (Author), Elisa eTellez (Author), Grant S. Mastick (Author), Elisa eTamariz (Author), Alfredo eVarela-Echavarria (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Nigrostriatal pathway (NSP) is formed by dopaminergic axons that project from the ventral midbrain to the dorsolateral striatum as part of the medial forebrain bundle. Previous studies have implicated chemotropic proteins in the formation of the NSP during development but little is known of the...