From tryptamine to the discovery of efficient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders

• Main Authors: Junbo Wu (Author), Honghua Zhang (Author), Yuying Wang (Author), Gaofeng Yin (Author), Qien Li (Author), Linsheng Zhuo (Author), Hongjin Chen (Author), Zhen Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel class of benzyl-free and benzyl-substituted carbamylated tryptamine derivatives (CDTs) was designed and synthesized to serve as effective building blocks for the development of novel multi-target directed ligands (MTDLs) for the treatment of neurological disorders linked to cholinesterase (C...