Cover Image

Forced Degradation Studies and Development and Validation of HPLC-UV Method for the Analysis of Velpatasvir Copovidone Solid Dispersion

Analytical methods for the drug substance and degradation products (DPs) are validated by performing forced degradation studies. Forced degradation studies of Velpatasvir (VEL) drug substance and Velpatasvir copovidone solid dispersion (VEL-CSD) were performed under the stressed alkaline, acidic, ox...

Full description

Saved in:

Bibliographic Details
Main Authors:	Bakht Zaman (Author), Waseem Hassan (Author), Adnan Khan (Author), Ayesha Mushtaq (Author), Nisar Ali (Author), Muhammad Bilal (Author), Dina A. Ahmed (Author)
Format:	Book
Published:	MDPI AG, 2022-07-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Selective Laser Sintering of Solid Oral Dosage Forms with Copovidone and Paracetamol Using a CO<sub>2</sub> Laser
by: Yanis A. Gueche, et al.
Published: (2021)

Taxifolin stability: In silico prediction and in vitro degradation with HPLC-UV/UPLC-ESI-MS monitoring
by: Fernanda Cristina Stenger Moura, et al.
Published: (2021)

Forced degradation of gliquidone and development of validated stability-indicating HPLC and TLC methods
by: Mohamed Refaat El-ghobashy, et al.
Published: (2018)

Simultaneous determination of steroid drugs in the ointment via magnetic solid phase extraction followed by HPLC-UV
by: Yadollah Yamini, et al.
Published: (2018)

RP-HPLC method development and validation for the quantification of Efonidipine hydrochloride in HME processed solid dispersions
by: Ashish S. Rajput, et al.
Published: (2020)

Formulating a heat- and shear-labile drug in an amorphous solid dispersion: Balancing drug degradation and crystallinity
by: Daniel A. Davis, Jr, et al.
Published: (2021)

Surface Solid Dispersion and Solid Dispersion of Meloxicam: Comparison and Product Development
by: Mayank Chaturvedi, et al.
Published: (2017)

The Development and Validation of HPLC-UV method for Analysis of Ciprofloxacin in serum and aqueous Humour
by: Abbas khan, et al.
Published: (2011)

In vitro antifungal, anti-oxidant and HPLC analysis of the extracts of Physalis philadelphica
by: Wajid Khan, et al.
Published: (2017)

Antifungal, anti-yeast, anti-oxidant and HPLC analysis of different solvent extracted samples from Calamus aromaticus leaves
by: Bilal Muhammad Khan, et al.
Published: (2015)

The Development and Validation of HPLC-UV method for Analysis of Ciprofloxacin in serum and aqueous Humour
by: Abbas khan1, Zafar Iqbal1 , Jamshaid Ali Khan1, Muhammad Imran Khan1, Ghulam Sarwar khan2 Muhammad Bilal3, Tahir Mehmood Khan4
Published: (2011)

UV Spectrophotometric method for determination of posaconazole: comparison to HPLC
by: Andressa S. Bitencourt, et al.
Published: (2015)

Enhancement of dissolution of Telmisartan through use of solid dispersion technique surface solid dispersion
by: Bhumika Patel, et al.
Published: (2012)

Determination of ethinylestradiol and levonorgestrel in oral contraceptives with HPLC methods with UV detection and UV/fluorescence detection
by: Zorica Arsova-Sarafinovska, et al.
Published: (2006)

Investigation of antioxidant compounds in commercial pomegranate molasses products using matrix-solid phase dispersion extraction coupled with HPLC
by: Y.T. Kamal, et al.
Published: (2018)

Development and validation by statistical treatment of stability indicating RP-HPLC method for quantification of Orlistat in Orlistat-loaded solid dispersion
by: Kiran Singh Sharma, et al.
Published: (2021)

A study of the formation of magnetically active solid dispersions of phenacetin using atomic and magnetic force microscopy
by: Liana Stanislavovna Usmanova, et al.
Published: (2017)

Stability-indicating HPLC method for determination of amiodarone hydrochloride and its impurities in tablets: a detailed forced degradation study
by: Ana Silva Coelho, et al.
Published: (2020)

Comparison of microbiological assay and HPLC-UV for determination of fluconazole in capsules
by: Kelly Marques Queiroz, et al.
Published: (2009)

Simultaneous HPLC-UV analysis of telmisartan and hydrochlorothiazide in human plasma
by: Ismail Salama
Published: (2011)

Optimizing extrusion processes and understanding conformational changes in itraconazole amorphous solid dispersions using in-line UV-Vis spectroscopy and QbD principles
by: Hetvi Triboandas, et al.
Published: (2024)

Development and Evaluation of Solid Dispersion-Based Sublingual Films of Nisoldipine
by: Yahya Alhamhoom, et al.
Published: (2023)

RP-HPLC method development and validation for bedaquiline fumarate to evaluate its forced degradation behaviour and stability in official dissolution media
by: Vishwas Pardhi, et al.
Published: (2020)

Chemical fingerprinting and quantitative analysis of a <it>Panax notoginseng </it>preparation using HPLC-UV and HPLC-MS
by: Shao Qing, et al.
Published: (2011)

Nanoseeded Desupersaturation and Dissolution Tests for Elucidating Supersaturation Maintenance in Amorphous Solid Dispersions
by: Gulenay Guner, et al.
Published: (2023)

Recent Progress in Solid Dispersion Technology
by: Kawakami, Kohsaku
Published: (2019)

EFFECT OF SOLID DISPERSIONS ON THE SOLUBILITY OF METRONIDAZOLE
by: I. I. Krasnyuk (Jr.), et al.
Published: (2021)

Atorvastatin solid dispersion for bioavailability enhancement
by: Shamsuddin, et al.
Published: (2016)

Processing Impact on Performance of Solid Dispersions
by: Dan Zhang, et al.
Published: (2018)

Photo-degradation of atrazine in water using UV and investigating its by-products
by: Zohre Moeini, et al.
Published: (2018)

Degradation of 17β-estradiol by UV/persulfate in different water samples
by: Yunjie Zhu, et al.
Published: (2021)

LCâUV and LCâMS evaluation of stress degradation behavior of desvenlafaxine
by: Shubhangi M. Pawar, et al.
Published: (2012)

Efficacy and Safety of Generic Sofosbuvir Plus Daclatasvir and Sofosbuvir/Velpatasvir in HCV Genotype 3-Infected Patients: Real-World Outcomes From Pakistan
by: Saima Mushtaq, et al.
Published: (2020)

Simple HPLC-UV Method for Piperacillin/Tazobactam Assay in Human Plasma
by: Khaled Abdelkawy, et al.
Published: (2023)

Development and validation of HPLC and UV spectrophotometric methods for the determination of lumiracoxib in tablets
by: V. P. SOUSA, et al.
Published: (2009)

Development and validation of HPLC and UV spectrophotometric methods for the determination of lumiracoxib in tablets
by: T.S. Moreira, et al.
Published: (2008)

Analytical quality by design-based RP-HPLC method for quantification of pioglitazone and candesartan cilexetil in bilayer tablet and its forced degradation studies
by: Hephzibah Kola, et al.
Published: (2023)

Solid Dispersions for Drug Delivery Applications and Preparation Methods
Published: (2022)

Sofosbuvir/velpatasvir regimen promises an effective pan-genotypic hepatitis C virus cure
by: Mir F, et al.
Published: (2017)

Eight-week treatment with sofosbuvir/velpatasvir may be effective in curing hepatitis C in children
by: Maria Pokorska-Śpiewak, et al.
Published: (2024)