Butorphanol: Effects of a Prototypical Agonist-Antagonist Analgesic on κ-Opioid Receptors

• Prif Awduron: Stephen Commiskey (Awdur), Lir-Wan Fan (Awdur), Ing K. Ho (Awdur), Rob W. Rockhold (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2005-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The opioid analgesic, butorphanol (17-cyclobutylmethyl-3,14-dihydroxymorphinan) tartrate is a prototypical agonist-antagonist opioid analgesic agent whose potential for abuse has been the cause of litigation in the United States. With a published affinity for opioid receptors in vitro of 1:4:25 (µ:δ...