Monitoring model drug microencapsulation in PLGA scaffolds using X-ray powder d

The microencapsulation of three model drugs; metronidazole, paracetamol and sulphapyridine into Poly (dl-Lactide-Co-Glycolide) (PLGA) scaffolds were probed using X-ray Powder Diffraction (XRPD). Changes in the diffraction patterns of the PLGA scaffolds after encapsulation was suggestive of a chemica...

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Main Authors: Adeyinka Aina (Author), Manish Gupta (Author), Yamina Boukari (Author), Andrew Morris (Author), Nashiru Billa (Author), Stephen Doughty (Author)
Format: Book
Published: Elsevier, 2016-03-01T00:00:00Z.
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100 1 0 |a Adeyinka Aina  |e author 
700 1 0 |a Manish Gupta  |e author 
700 1 0 |a Yamina Boukari  |e author 
700 1 0 |a Andrew Morris  |e author 
700 1 0 |a Nashiru Billa  |e author 
700 1 0 |a Stephen Doughty  |e author 
245 0 0 |a Monitoring model drug microencapsulation in PLGA scaffolds using X-ray powder d 
260 |b Elsevier,   |c 2016-03-01T00:00:00Z. 
500 |a 1319-0164 
500 |a 10.1016/j.jsps.2015.03.015 
520 |a The microencapsulation of three model drugs; metronidazole, paracetamol and sulphapyridine into Poly (dl-Lactide-Co-Glycolide) (PLGA) scaffolds were probed using X-ray Powder Diffraction (XRPD). Changes in the diffraction patterns of the PLGA scaffolds after encapsulation was suggestive of a chemical interaction between the pure drugs and the scaffolds and not a physical intermixture. 
546 |a EN 
690 |a Encapsulation 
690 |a PLGA 
690 |a Model drugs 
690 |a XRPD 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Saudi Pharmaceutical Journal, Vol 24, Iss 2, Pp 227-231 (2016) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S131901641500078X 
787 0 |n https://doaj.org/toc/1319-0164 
856 4 1 |u https://doaj.org/article/e13cb0c6653f4e29bf5ad6310f5bb36f  |z Connect to this object online.