MDMA-Induced Dissociative State not Mediated by the 5-HT2A Receptor

• Main Authors: Drew J. Puxty (Author), Johannes G. Ramaekers (Author), Rafael de la Torre (Author), Magí Farré (Author), Neus Pizarro (Author), Mitona Pujadas (Author), Kim P. C. Kuypers (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previous research has shown that a single dose of MDMA induce a dissociative state, by elevating feelings of depersonalization and derealization. Typically, it is assumed that action on the 5-HT2A receptor is the mechanism underlying these psychedelic experiences. In addition, other studies have sho...