Delivery of GalNAc-Conjugated Splice-Switching ASOs to Non-hepatic Cells through Ectopic Expression of Asialoglycoprotein Receptor
Splice-switching antisense oligonucleotides (ASOs) are promising therapeutic tools to target various genetic diseases, including cancer. However, in vivo delivery of ASOs to orthotopic tumors in cancer mouse models or to certain target tissues remains challenging. A viable solution already in use is...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2019-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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